Author's response to reviews Title:Bubble CPAP to support preterm infants in rural Rwanda: a retrospective cohort study Authors:

Bubble CPAP to support preterm infants in rural Rwanda: a retrospective cohort study

BACKGROUND Complications from premature birth contribute to 35% of neonatal deaths globally; therefore, efforts to improve clinical outcomes of preterm (PT) infants are imperative. Bubble continuous positive airway pressure (bCPAP) is a low-cost, effective way to improve the respiratory status of preterm and very low birth weight (VLBW) infants. However, bCPAP remains largely inaccessible in re...

Author's response to reviews Title: Secular trends in pediatric antiretroviral treatment programs in rural and urban Zambia: a retrospective cohort study Authors:

Author's response to reviews Title: Calcium, phosphate, magnesium, and alkaline phosphatase gestational age-specific reference intervals for preterm infants Authors:

Title: Calcium, phosphate, magnesium, and alkaline phosphatase gestational age-specific reference intervals for preterm infants

Incidence and Outcome of CPAP Failure in Preterm Infants.

BACKGROUND AND OBJECTIVES Data from clinical trials support the use of continuous positive airway pressure (CPAP) for initial respiratory management in preterm infants, but there is concern regarding the potential failure of CPAP support. We aimed to examine the incidence and explore the outcomes of CPAP failure in Australian and New Zealand Neonatal Network data from 2007 to 2013. METHODS Da...

Strategies to reduce mechanical ventilation and bronchopulmonary dysplasia in preterm infants.

As evidenced by the recent trials, a large proportion of infants can be adequately managed with CPAP, with comparable rates of BPD to those achieved in mechanically ventilated infants.2,3 These trials also made clear that a significant proportion of infants initially started on CPAP eventually require mechanical ventilation, which was more evident among infants of lower gestational age. In the ...